Bioactivity | [D-Phe12]-Bombesin is a derivative of Bombesin (HY-P0195) and an antagonist for bombesin receptor with Ki of 4.7 μM. [D-Phe12]-Bombesin inhibits the Bombesin (HY-P0195)-induced amylase release, with IC50 of 4 μM[1]. |
CAS | 108437-87-2 |
Sequence | {Pyr}-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-{d-Phe}-Leu-Met-NH2 |
Shortening | {Pyr}-QRLGNQWAVG-{d-Phe}-LM-NH2 |
Formula | C74H112N22O18S |
Molar Mass | 1629.88 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Heinz-Erian P, et al., [D-Phe12]bombesin analogues: a new class of bombesin receptor antagonists. Am J Physiol. 1987 Mar;252(3 Pt 1):G439-42. |