PeptideDB

[D-Phe12]-Bombesin

CAS: 108437-87-2 F: C74H112N22O18S W: 1629.88

-Bombesin is a derivative of Bombesin (HY-P0195) and an antagonist for bombesin receptor with Ki of 4.7 μM. -Bombesin i
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Bioactivity [D-Phe12]-Bombesin is a derivative of Bombesin (HY-P0195) and an antagonist for bombesin receptor with Ki of 4.7 μM. [D-Phe12]-Bombesin inhibits the Bombesin (HY-P0195)-induced amylase release, with IC50 of 4 μM[1].
CAS 108437-87-2
Sequence {Pyr}-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-{d-Phe}-Leu-Met-NH2
Shortening {Pyr}-QRLGNQWAVG-{d-Phe}-LM-NH2
Formula C74H112N22O18S
Molar Mass 1629.88
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Heinz-Erian P, et al., [D-Phe12]bombesin analogues: a new class of bombesin receptor antagonists. Am J Physiol. 1987 Mar;252(3 Pt 1):G439-42.